20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8288 | 14-Deoxyandrographolide | Apoptosis , Others | |
14-Deoxyandrographolide is a bioactive compound of Andrographis paniculata with hepatoprotective efficacy. It desensitizes hepatocytes to TNF-α-mediated apoptosis through the release of TNFRSF1A release. | |||
TN4222 | Homoeriodictyol 7-O-β-D-glucoside | Homoeriodictyol 7-O-glucoside | Others , Platelet aggregation |
Homoeriodictyol 7-O-β-D-glucoside (Homoeriodictyol 7-O-glucoside) is a natural product from Viscum coloratum(Kom.)Nakai. Homoeriodictyol 7-O-β-D-glucoside is an antagonist of platelet-activating factor (PAF). | |||
T27102 | CV-6209 | ||
CV-6209 is a potent antagonist of the platelet-activating factor (PAF) receptor. | |||
T14007 | PAF-AN-1 | PAFR | |
PAF-AN-1 is a novel potent platelet-activating factor receptor (PAF) antagonist involved in the study of anaphylactic death. | |||
T10159 | 48740 RP | RP-48740,RP-55778,RP 55779,RP 55778 | PAFR , Platelet aggregation |
48740 RP (RP 55779) is an antagonist of platelet-activating factor. | |||
T15338 | Foropafant | SR27417 | Others , Platelet aggregation |
Foropafant (SR27417) is a highly potent and selective platelet-activating factor (PAF) receptor antagonist (Ki: 57 pM). Foropafant potently inhibits the PAF-induced aggregation of rabbit and human platelets. | |||
T28740 | SDZ-62-434 | SDZ 62 434,SDZ62434 | Platelet aggregation |
SDZ-62-434 is a platelet-activating factor inhibitor with antitumor activity that inhibits bombesin- and platelet-derived growth factor-induced DNA synthesis in quiescent Swiss 3T3 cells for the study of leukemia, human ... | |||
T28607 | Rocepafant | LAU 8080,LAU8080,BN 50730,LAU-8080,BN50730,BN-50730 | Platelet aggregation |
Rocepafant (LAU8080) is a platelet-activating factor (PAF) antagonist that attenuates hypoxic-ischemic brain damage in neonatal rats.Rocepafant inhibits tumor necrosis factor-Afa-mediated cytotoxicity in mouse L929 tumor... | |||
T17178 | Tulopafant | RP 59227 | PAFR |
Tulopafant (RP 59227) is a potent platelet-activating factor (PAF) antagonist that increases capillary patency and prolongs allograft heart survival. | |||
T16751 | Rilapladib | SB 659032 | Phospholipase |
Rilapladib (SB 659032) is a selective inhibitor of Lipoprotein-Associated Phospholipase A2(Lp-PLA2, IC50 = 230 pM) and an antagonist of the platelet activating factor receptor. | |||
T70084 | Dersalazine | Dersalazine Free Base | IL Receptor , Platelet aggregation |
Dersalazine (Dersalazine Free Base), an inhibitor of platelet-activating factor, exerts intestinal anti-inflammatory activity in different rodent types of colitis by down-regulating IL-17 expression, with potential effic... | |||
T77638 | BIRM 271 | Phospholipase , LTR | |
BIRM 271 is a novel arachidonic acid release inhibitor that blocks leukotriene B4 and platelet-activating factor biosynthesis in human neutrophils. BIRM 271 and BIRM 270 are enantiomers that inhibit the production of leu... | |||
TN1873 | Lirinidine | Others | |
(+)-Lirinidine has antioxidative activity, and it can significantly inhibit the proliferation of melanoma cells; it also shows potent inhibition of melanogenesis. Lirinidine exhibits significant inhibition of collagen, a... | |||
TN2322 | Yangambin | Calcium Channel , PAFR | |
Yangambin is a selective antagonist of the cardiovascular effects of platelet activating factor (PAF); it has hypotensive effect, which is probably due to a peripheral vasodilatation that involves, at least, the inhibiti... | |||
T19686 | SCH-37370 | Platelet aggregation | |
SCH-37370 is an effective and orally active dual antagonist of platelet-activating factor and histamine. Sch 37370 blocks the binding of [3H]pyrilamine to histamine-H1 receptors in rat brain membranes. Sch 37370 selectiv... | |||
T3979 | Emedastine | LY188695,Emadine | Histamine Receptor |
Emedastine (LY188695) is a second generation, selective histamine H1 receptor antagonist with anti-allergic activity. Emedastine reversibly and competitively blocks histamine by binding to H1 receptors, thus blocking its... | |||
T67959 | Pirodomast | Thrombin , Serine Protease | |
Pirodomast is a thromboxane A (TXA2) synthase inhibitor. Pirodomast inhibits leukotriene (LT) D4, C4, E4 formation and thromboxane B2 (TXB2) activity, but is weakly or ineffectively antagonistic to guinea pig bronchospas... | |||
T26876 | BN 52111 | BN-52111,BN52111 | |
BN 52111 is a platelet activating factor antagonist. | |||
T27821 | Lexipafant | ISV-611,GR-167089,DO-6,BB-882,DO6,BB882 | |
Lexipafant is a platelet-activating factor (PAF) receptor antagonist. | |||
T24321 | L 668750 | ||
L 668750 is an inhibitor of platelet-activating factor. |