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Search Results for " platelet activating factor "

20

Compounds

Cat No. Product Name Synonyms Targets
T8288 14-Deoxyandrographolide Apoptosis , Others
14-Deoxyandrographolide is a bioactive compound of Andrographis paniculata with hepatoprotective efficacy. It desensitizes hepatocytes to TNF-α-mediated apoptosis through the release of TNFRSF1A release.
TN4222 Homoeriodictyol 7-O-β-D-glucoside Homoeriodictyol 7-O-glucoside Others , Platelet aggregation
Homoeriodictyol 7-O-β-D-glucoside (Homoeriodictyol 7-O-glucoside) is a natural product from Viscum coloratum(Kom.)Nakai. Homoeriodictyol 7-O-β-D-glucoside is an antagonist of platelet-activating factor (PAF).
T27102 CV-6209
CV-6209 is a potent antagonist of the platelet-activating factor (PAF) receptor.
T14007 PAF-AN-1 PAFR
PAF-AN-1 is a novel potent platelet-activating factor receptor (PAF) antagonist involved in the study of anaphylactic death.
T10159 48740 RP RP-48740,RP-55778,RP 55779,RP 55778 PAFR , Platelet aggregation
48740 RP (RP 55779) is an antagonist of platelet-activating factor.
T15338 Foropafant SR27417 Others , Platelet aggregation
Foropafant (SR27417) is a highly potent and selective platelet-activating factor (PAF) receptor antagonist (Ki: 57 pM). Foropafant potently inhibits the PAF-induced aggregation of rabbit and human platelets.
T28740 SDZ-62-434 SDZ 62 434,SDZ62434 Platelet aggregation
SDZ-62-434 is a platelet-activating factor inhibitor with antitumor activity that inhibits bombesin- and platelet-derived growth factor-induced DNA synthesis in quiescent Swiss 3T3 cells for the study of leukemia, human ...
T28607 Rocepafant LAU 8080,LAU8080,BN 50730,LAU-8080,BN50730,BN-50730 Platelet aggregation
Rocepafant (LAU8080) is a platelet-activating factor (PAF) antagonist that attenuates hypoxic-ischemic brain damage in neonatal rats.Rocepafant inhibits tumor necrosis factor-Afa-mediated cytotoxicity in mouse L929 tumor...
T17178 Tulopafant RP 59227 PAFR
Tulopafant (RP 59227) is a potent platelet-activating factor (PAF) antagonist that increases capillary patency and prolongs allograft heart survival.
T16751 Rilapladib SB 659032 Phospholipase
Rilapladib (SB 659032) is a selective inhibitor of Lipoprotein-Associated Phospholipase A2(Lp-PLA2, IC50 = 230 pM) and an antagonist of the platelet activating factor receptor.
T70084 Dersalazine Dersalazine Free Base IL Receptor , Platelet aggregation
Dersalazine (Dersalazine Free Base), an inhibitor of platelet-activating factor, exerts intestinal anti-inflammatory activity in different rodent types of colitis by down-regulating IL-17 expression, with potential effic...
T77638 BIRM 271 Phospholipase , LTR
BIRM 271 is a novel arachidonic acid release inhibitor that blocks leukotriene B4 and platelet-activating factor biosynthesis in human neutrophils. BIRM 271 and BIRM 270 are enantiomers that inhibit the production of leu...
TN1873 Lirinidine Others
(+)-Lirinidine has antioxidative activity, and it can significantly inhibit the proliferation of melanoma cells; it also shows potent inhibition of melanogenesis. Lirinidine exhibits significant inhibition of collagen, a...
TN2322 Yangambin Calcium Channel , PAFR
Yangambin is a selective antagonist of the cardiovascular effects of platelet activating factor (PAF); it has hypotensive effect, which is probably due to a peripheral vasodilatation that involves, at least, the inhibiti...
T19686 SCH-37370 Platelet aggregation
SCH-37370 is an effective and orally active dual antagonist of platelet-activating factor and histamine. Sch 37370 blocks the binding of [3H]pyrilamine to histamine-H1 receptors in rat brain membranes. Sch 37370 selectiv...
T3979 Emedastine LY188695,Emadine Histamine Receptor
Emedastine (LY188695) is a second generation, selective histamine H1 receptor antagonist with anti-allergic activity. Emedastine reversibly and competitively blocks histamine by binding to H1 receptors, thus blocking its...
T67959 Pirodomast Thrombin , Serine Protease
Pirodomast is a thromboxane A (TXA2) synthase inhibitor. Pirodomast inhibits leukotriene (LT) D4, C4, E4 formation and thromboxane B2 (TXB2) activity, but is weakly or ineffectively antagonistic to guinea pig bronchospas...
T26876 BN 52111 BN-52111,BN52111
BN 52111 is a platelet activating factor antagonist.
T27821 Lexipafant ISV-611,GR-167089,DO-6,BB-882,DO6,BB882
Lexipafant is a platelet-activating factor (PAF) receptor antagonist.
T24321 L 668750
L 668750 is an inhibitor of platelet-activating factor.
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